Pozdnyakova ON, Nemchaninova OB, Lykova SG et al.
Novosibirsk State Medical University, Ministry of Health of Russia, Novosibirsk, Russia.
Terapevticheskii arkhiv. 2017.
To determine the clinical features of skin diseases developing in the presence of metabolic disturbances in patients with chronic diffuse liver diseases.A total of 368 patients with different clinical forms of hepatopathy were comprehensively examined.817 cases of seborrhea, skin itch, xerodermia, xanthomatosis, and dyschromia were detected in 318 (86.4%) patients.The prevalence and intensity of cutaneous manifestations depended on the nature of the pathological liver process and indirectly testified to its severity and activity. The symptoms of skin diseases were most pronounced in patients with autoimmune liver lesions, chronic toxic hepatitis, and cirrhosis.