Downstaging of bilobar hepatocellular carcinoma after radioembolization with (90)Y microspheres as a bridge to liver transplantation.

Reguera-Berenguer L, Orcajo-Rincón J, Rotger-Regí A et al.

Servicio de Medicina Nuclear, Hospital General Universitario Gregorio Marañón, Madrid, España. Electronic address:

Revista espanola de medicina nuclear e imagen molecular. Mar 2017.

Hepatic radioembolization with (90)Y is an increasingly widely used locoregional therapy in the treatment of hepatocellular carcinoma. Its potential benefit has recently been described as a downstaging treatment, achieving a decreased tumour burden and allowing patients to be rescued for more radical treatments, such as liver transplantation. The case is presented of a patient diagnosed with multifocal bilobar hepatocellular carcinoma, Barcelona Clinic Liver Cancer (BCLC) intermediate stage, in whom treatment with (90)Y achieved a satisfactory radiological response with a very significant reduction of tumour burden, allowing rescue with liver transplantation.